老年冠状动脉支架植入术:纵向结果在广泛的患者治疗与新的和更实用的方法。

M D Bage, W B Bauman, R Gupta, K E Berkovitz, A P Ormond, F Grigera, R A Josephson
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引用次数: 3

摘要

112个冠状动脉内支架(83个Palmaz-Schatz支架,25个胆道支架,4个Gianturco-Roubin支架)被放置在87例(51.7%男性)年龄>或= 70岁的患者(70-93;平均76.1)。所有支架置入均采用高压充气(平均17.4 +/- 2 atm),无需血管内超声。所有患者均接受阿司匹林和噻氯匹定抗血小板治疗。7名患者在医生的判断下额外接受华法林治疗。没有患者被排除在分析之外,无论其表现(40%急性心肌梗死和12.6%救助)或并发症。有4人死亡,2人在医院接受靶血管再介入治疗。一次再干预(紧急救助)发展为非q波心肌梗死。华法林组出血、血管并发症和住院时间均大于华法林组。无事件生存率为83.9%,平均随访8.6个月。因此,大范围的老年患者可以在没有血管内超声的情况下接受支架植入,通常不使用华法林,其结果与在特定人群中使用更标准治疗的结果相当。
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Coronary stenting in the elderly: longitudinal results in a wide spectrum of patients treated with a new and more practical approach.

One hundred-twelve intracoronary stents (83 Palmaz-Schatz, 25 biliary, and 4 Gianturco-Roubin) were placed in 87 (51.7% male) patients aged > or = 70 years (70-93; mean 76.1) during a 1-year period. All stents were deployed using high-pressure inflation (mean 17.4 +/- 2 atm) without intravascular ultrasound. All patients received antiplatelet therapy with aspirin and ticlopidine. Seven patients additionally received warfarin at the physician's discretion. No patient was excluded from analysis regardless of presentation (40% acute myocardial infarction and 12.6% bailout) or complication. There were four deaths and two target vessel reinterventions in-hospital. One reintervention (a bailout) developed a non-Q-wave myocardial infarction. Bleeding, vascular complications, and length of stay were all greater for the warfarin group. The event-free survival rate was 83.9%, at an average of 8.6 months follow-up. A wide range of elderly patients can thus undergo stenting without intravascular ultrasound, usually without warfarin, yielding results comparable to those with more standard therapy in select populations.

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