甲氨蝶呤在儿童中的应用。

Bulletin on the rheumatic diseases Pub Date : 1998-08-01
M H Passo, P J Hashkes
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引用次数: 0

摘要

甲氨蝶呤仍然是治疗JRA最安全、最有效的二线药物。此外,它对儿童的其他炎症也很有用。仔细的教育是必要的,特别是关于实验室检查的重要性和避免合并症,如怀孕和酒精引起的肝损伤。卫生保健提供者应该自在地与儿童和青少年讨论这些问题。
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Use of methotrexate in children.

Methotrexate continues to be the safest and most efficacious second-line drug for the treatment of JRA. In addition, it is useful in other inflammatory conditions in children. Careful education is necessary, particularly with regard to the importance of laboratory tests and the avoidance of comorbidity such as pregnancy and alcohol-induced liver injury. Health care providers should be comfortable discussing these issues with children and adolescents.

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