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引用次数: 0

摘要

现在人们普遍认为,因酒精相关性肝病接受肝移植的患者与因其他适应症接受肝移植的患者存活率相似。肝移植前戒酒对确保肝脏不会恢复很重要,但移植前戒酒的时间是不确定的。用于评估酒精性肝病患者的预后模型已经开发出来,但彼此之间的相关性很差。移植后恢复饮酒并不罕见,尽管移植失败或损伤并不常见。然而,酒精相关性肝病正逐渐成为肝移植的适应症。由于潜在候选国的数量超过了捐助国的数量,将需要某种形式的定量配给。与其他适应症相比,一般公众对酒精性肝病移植的重视程度较低,分配捐赠肝脏的人需要考虑这一点。
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Transplantation for alcoholic liver disease: a perspective from Europe.

It is now accepted that patients who receive a liver transplant for alcohol-related liver disease have a rate of survival similar to those who receive grafts for other indications. Abstinence from alcohol before liver transplantation is important in ensuring that the liver will not recover, but the period of abstinence required before transplantation is undertaken is uncertain. Prognostic models for assessing patients with alcoholic liver disease have been developed but correlate poorly with each other. A return to alcohol consumption after transplantation is not uncommon, although graft failure or damage is uncommon. However, alcohol-related liver disease is becoming an increasing indication for liver transplantation. As the number of potential candidates exceeds the supply of donors, some form of rationing will be required. The general public places a lower priority on transplantation for alcoholic liver disease than for other indications, and this will need to be considered by those who allocate the donor livers.

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