内源性红系集落形成对原发性血小板增多症的预后和诊断价值。

Hematology and cell therapy Pub Date : 1998-08-01
M Ciaudo, J M Hadjez, I Teyssandier, E Coly, R Zittoun, J P Marie
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引用次数: 0

摘要

内源性红细胞集落(EECs)是真性红细胞增多症(PV)的典型特征,可在原发性血小板增多症(ET)中观察到。对34例未经治疗的明确ET患者进行红系祖细胞培养,35%的病例显示EECs。在培养后平均4年的随访中,12例EECs(+)和22例EECs(-)患者在血栓形成或出血性并发症方面没有任何差异,唯一一例出现红细胞生成的患者是EECs(-)组。
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Prognostic and diagnostic value of endogenous erythroid colony formation in essential thrombocythemia.

Endogenous erythroid colonies (EECs), a typical characteristic of polycythemia vera (PV), could be observed in essential thrombocythemia (ET). Erythroid progenitors culture carried out in 34 previously untreated patients with unequivocal ET showed EECs in 35% of the cases. During a mean follow up of 4 years after the culture, the 12 EECs(+) and the 22 EECs(-) patients did not show any difference for a thrombotic or haemorrhagic complication, and the only one patient who showed an involvement of erythropoiesis was in the EECs(-) group.

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