计算机轴位断层串联和卵泡(CATTO)剂量测定:膀胱和直肠剂量的三维评估。

W J Gebara, K J Weeks, C A Hahn, G S Montana, M S Anscher
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引用次数: 17

摘要

本研究的目的是比较使用两种不同剂量测定系统的宫颈癌近距离放射治疗的膀胱和直肠剂量率:传统的基于正交x线摄影的剂量测定与计算机轴向断层摄影串联和卵泡(CATTO)剂量测定。22例宫颈癌患者使用兼容Fletcher-Suit-Delclos的计算机断层扫描设备接受放射治疗的近距离治疗。共进行了27次种植。使用CATTO系统植入物的平均膀胱最大剂量(Bmax)为85.8 cGy/hr,而使用传统剂量学的平均剂量为42.6 cGy/hr, (P < 0.005)。使用CATTO系统的平均最大直肠剂量(r)为59.2 cGy/hr,而使用传统系统的平均最大直肠剂量为46.3 cGy/hr (P < 0.05)。传统的选择点确定膀胱和直肠剂量率的方法低估了所有病例的真实Bmax和大多数病例的r。根据文献发表的并发症发生率,直肠和膀胱,尤其是膀胱的最大耐受剂量可能比之前认为的要高。
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Computed axial tomography tandem and ovoids (CATTO) dosimetry: three-dimensional assessment of bladder and rectal doses.

The purpose of this work is to compare bladder and rectal dose rates in brachytherapy for carcinoma of the cervix using two different dosimetry systems: traditional orthogonal radiograph-based dosimetry vs. computed axial tomography tandem and ovoids (CATTO) dosimetry. Twenty-two patients with carcinoma of the uterine cervix received the brachytherapy component of their radiotherapy with a computed-tomography compatible Fletcher-Suit-Delclos device. A total of 27 implants were performed. The average maximum bladder dose (Bmax) for the implants was 85.8 cGy/hr using the CATTO system as compared to 42.6 cGy/hr using traditional dosimetry, (P < 0.005). The average maximum rectal dose (R.) using the CATTO system was 59.2 cGy/hr as compared with 46.3 cGy/hr using the traditional system (P < 0.05). The traditional methods for choosing points to determine bladder and rectal dose rates underestimated the true Bmax in all cases and the R. in most. Based on the complication rates published in the literature, it is likely that the maximum tolerance dose of both the rectum and bladder, but especially the bladder, is higher than previously thought.

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