血管内主动脉瘤修复后纵动脉瘤收缩:中晚期并发症的一个来源。

P Harris, J Brennan, J Martin, D Gould, A Bakran, G Gilling-Smith, J Buth, E Gevers, D White
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引用次数: 27

摘要

目的:报道腹主动脉瘤(AAA)血管内修复术后迟发性并发症的发生率,以及这些并发症与腔囊和移植物形态学改变的关系。方法:26例接受Vanguard植入术治疗的AAA级患者均完成1年或1年的随访。术后血管造影和三维重建的螺旋CT (CT)扫描与1年的图像进行比较,以确定动脉瘤囊和内移植物的形态学变化。这些变化与研究组术后1至12个月间发生的并发症有关。结果:血管造影显示18例(69%)患者内移植物屈曲,10例(38%)患者内移植物剧烈倾斜或扭结。CT扫描结果显示,未变形的内移植物囊长度的平均变化为+6.6 mm。屈曲型内移植物囊长度的平均变化为-3.1 mm,而扭结型内移植物囊长度的平均变化为-6.2 mm (p < 0.002, Student’st检验)。5例(19%)患者均采用扭曲的内移植物,由于组件分离、远端支架迁移和急性成角,出现了晚期(1至12个月)并发症(4例内漏和1例移植物肢体血栓)。近端支架未见移位。仅在一根管内移植物中观察到移植物的伸长(流线测量)。结论:在本研究中,69%的患者血管内动脉瘤修复后囊的纵向收缩导致1年内内移植物屈曲或扭结。这似乎是迟发性并发症的一个重要来源。
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Longitudinal aneurysm shrinkage following endovascular aortic aneurysm repair: a source of intermediate and late complications.

Purpose: To report the incidence of delayed complications following endovascular abdominal aortic aneurysm (AAA) repair and the relationship of these sequelae to morphological changes in the sac and endograft.

Methods: Twenty-six AAA patients treated with Vanguard endografts had completed > or = 1-year follow-up. Postoperative angiograms and spiral computed tomographic (CT) scans with 3-dimensional reconstruction were compared to the 1-year images to determine morphological changes in the aneurysm sac and the endograft. These changes were then related to complications occurring between 1 and 12 months postoperatively in the study group.

Results: Comparison of angiograms uncovered endograft buckling in 18 (69%) patients and acutely angled or kinked endografts in 10 (38%). Measurements from the CT scans found that undistorted endografts had a mean change in sac length of +6.6 mm. Mean sac length change in buckled endografts was -3.1 mm, while kinked endografts displayed a mean change of -6.2 mm (p < 0.002, Student's t-test). Five (19%) patients, all with distorted endografts, demonstrated late (1 to 12 months) complications (4 endoleaks and 1 graft limb thrombosis) owing to component separation, distal stent migration, and acute angulation. No movement in the proximal stent was observed. Elongation of the endograft (flow line measurement) was observed in one tube graft only.

Conclusions: In this study, longitudinal shrinkage of the sac following endovascular aortic aneurysm repair led to buckling or kinking of the endograft within 1 year in 69% of patients. This appears to be an important source of delayed complications.

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