A Morohashi, M Satake, H Naoki, H F Kaspar, Y Oshima, T Yasumoto
{"title":"从绿壳贻贝(Perna canaliculus)中分离的Brevetoxin B4,是纽西兰造成贝类神经毒性中毒的主要毒素。","authors":"A Morohashi, M Satake, H Naoki, H F Kaspar, Y Oshima, T Yasumoto","doi":"10.1002/(sici)1522-7189(199903/04)7:2<45::aid-nt34>3.0.co;2-h","DOIUrl":null,"url":null,"abstract":"<p><p>A new brevetoxin B analog, brevetoxin B4 (BTXB4), was isolated as the major toxin in greenshell mussels, Perna canaliculus, collected in New Zealand at the time of the neurotoxic shellfish poisoning incident. The new analog accounted for nearly two-thirds of the mouse lethality of the shellfish and was determined to be a mixture of N-myristoyl-BTXB2 and N-palmitoyl-BTXB2.</p>","PeriodicalId":18777,"journal":{"name":"Natural toxins","volume":"7 2","pages":"45-8"},"PeriodicalIF":0.0000,"publicationDate":"1999-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"73","resultStr":"{\"title\":\"Brevetoxin B4 isolated from greenshell mussels Perna canaliculus, the major toxin involved in neurotoxic shellfish poisoning in New Zealand.\",\"authors\":\"A Morohashi, M Satake, H Naoki, H F Kaspar, Y Oshima, T Yasumoto\",\"doi\":\"10.1002/(sici)1522-7189(199903/04)7:2<45::aid-nt34>3.0.co;2-h\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>A new brevetoxin B analog, brevetoxin B4 (BTXB4), was isolated as the major toxin in greenshell mussels, Perna canaliculus, collected in New Zealand at the time of the neurotoxic shellfish poisoning incident. The new analog accounted for nearly two-thirds of the mouse lethality of the shellfish and was determined to be a mixture of N-myristoyl-BTXB2 and N-palmitoyl-BTXB2.</p>\",\"PeriodicalId\":18777,\"journal\":{\"name\":\"Natural toxins\",\"volume\":\"7 2\",\"pages\":\"45-8\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1999-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"73\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Natural toxins\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1002/(sici)1522-7189(199903/04)7:2<45::aid-nt34>3.0.co;2-h\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Natural toxins","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1002/(sici)1522-7189(199903/04)7:2<45::aid-nt34>3.0.co;2-h","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Brevetoxin B4 isolated from greenshell mussels Perna canaliculus, the major toxin involved in neurotoxic shellfish poisoning in New Zealand.
A new brevetoxin B analog, brevetoxin B4 (BTXB4), was isolated as the major toxin in greenshell mussels, Perna canaliculus, collected in New Zealand at the time of the neurotoxic shellfish poisoning incident. The new analog accounted for nearly two-thirds of the mouse lethality of the shellfish and was determined to be a mixture of N-myristoyl-BTXB2 and N-palmitoyl-BTXB2.