2多囊卵巢综合征的外科治疗

MD, FRCSC, FACOG Togas Tulandi (Professor of Obstetrics and Gynecology, Director), MD Sundus Al Took (Fellow of Reproductive Endocrinology and Infertility)
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引用次数: 15

摘要

本章的目的是回顾在不孕妇女多囊卵巢综合征的手术管理的作用。通过计算机medline检索确定相关研究及其参考文献。迄今为止,尚无腹腔镜卵巢钻孔技术的标准化。然而,结果似乎是有希望的,排卵率在70%到90%之间,怀孕率为70%。克罗米芬柠檬酸盐仍然是第一线治疗诱导排卵不孕妇女多囊卵巢综合征。腹腔镜卵巢钻孔可以提供给克罗米芬耐药的女性,特别是那些对促性腺激素治疗无效或经历过卵巢过度刺激综合征的女性。卵巢钻孔后的妊娠率与促性腺激素治疗的妊娠率相当。然而,在获得更完整和长期的数据之前,在提供这种治疗时必须谨慎。
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2 Surgical management of polycystic ovarian syndrome

The objective of this chapter is to review the role of surgical management of polycystic ovarian syndrome in infertile women. Pertinent studies and their references were identified through computer medline search. To date there is no standardization of the technique of laparoscopic ovarian drilling. However, it appears that the results are promising, with a high ovulation rate ranging between 70% and 90% and a pregnancy rate of 70%. Clomiphene citrate remains the first line of treatment to induce ovulation in infertile women with polycystic ovarian syndrome. Laparoscopic ovarian drilling can be offered to clomiphene-resistant women, especially to those who have also failed to respond to gonadotrophin treatment or who have experienced ovarian hyperstimulation syndrome. It appears that the pregnancy rate after ovarian drilling is comparable with that for gonadotrophin therapy. However, until more complete and long-term data are available, caution must be exercised when offering this type of treatment.

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