【原发性血管成形术中球囊扩张与支架置入的比较研究】。

J Frade García, A Carrillo Anaya, R Alcocer Muñoz, L A Mata
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引用次数: 0

摘要

目的:探讨原发性血管成形术(PA)和新支架置入术治疗急性心肌梗死的效果。材料与方法:163例患者临床诊断为心肌梗死,平均症状发作时间为2.5小时。他们被分为两组:100例仅使用球囊的PA (I组)和63例使用初级支架(II组)(63例使用85个支架)。II组采用高压技术(14 ~ 16atm),所有患者均给予水杨酸和噻氯匹定治疗。两组进行比较。结果:临床特征、梗死部位及梗死相关动脉相似,均以左前降支为主。II组的临床成功率更高(97% vs 87%),并发症发生率是I组的3倍(9% vs 3%)。I组平均随访57个月,临床和/或血管造影再狭窄率为21%,而II组随访12个月,未发现任何再狭窄病例。结论:支架在PA中的应用改善了气囊手术的效果。在心源性休克时进行手术的患者成功率更高,并发症更少,生存率更高。
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[Comparative study of balloon dilatation and stent placement in primary angioplasty].

Objective: To communicate our results with primary angioplasty (PA) and stenting de novo in acute myocardial infarction.

Material and methods: 163 patients (pts) had clinical diagnosis of MI with an average onset time of symptoms of 2.5 hours. They were divided in two groups: 100 pts with PA using only balloon (group I) and 63 pts with primary stenting (group II) (63 pts with 85 stents). A high pressure technique (14-16 atm) was used in group II and all pts were on salicylic acid and ticlopidine. Both groups were compared.

Results: Clinical characteristics, infarct location and infarct related-artery were similar, being left anterior descending the more frequently vessel involved. Clinical success rate was higher in group II (97% vs 87%) and complication rate was threefold higher in group I (9% vs 3%). A mean follow up of 57 months in group I showed a 21% clinical and/or angiographic restenosis rate, while the 12 months follow up in group II failed to show any case of restenosis at all.

Conclusions: The use of stents in PA improves the results achieved with balloon procedures. There is a greater success rate, less complications and better survival patients who had the procedure while being in cardiogenic shock.

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