口服给药技术的最新进展

Srikonda Venkateswara Sastry, Janaki Ram Nyshadham, Joseph A. Fix
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引用次数: 636

摘要

尽管存在诸多缺点,口服给药仍是首选的给药途径。近年来出现了具有改进性能、患者依从性和提高质量的新技术。口服快速分散剂型、三维打印(3DP)和静电涂层是几种现有技术的几个例子,它们具有适应药物的各种物理化学、药代动力学和药效学特性的潜力。本文对这三种技术进行了全面的回顾。
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Recent technological advances in oral drug delivery – a review

Despite disadvantages, oral drug delivery remains the preferred route of drug delivery. Novel technologies with improved performance, patient compliance, and enhanced quality have emerged in the recent past. Oral fast-dispersing dosage forms, three-dimensional Printing (3DP) and electrostatic coating are a few examples of a few existing technologies with the potential to accommodate various physico-chemical, pharmacokinetic and pharmacodynamic characteristics of drugs. This article provides a comprehensive review of these three technologies.

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