听神经瘤不完全切除后复发。

H K El-Kashlan, H Zeitoun, H A Arts, J T Hoff, S A Telian
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引用次数: 113

摘要

目的:探讨听神经瘤不完全切除术后复发的风险。研究设计:回顾性病例回顾。环境:三级转诊中心。患者:1988年1月至1993年12月间,39例患者行听神经瘤不完全切除术,随访时间最短3.5年,平均6.2年(范围3.5-10.2年)。干预措施:定期随访。每年使用计算机轴向断层扫描或磁共振成像。主要结局指标:残留肿瘤的生长情况,通过随访影像学检查其最大尺寸的增加来确定,以及是否需要额外的治疗。结果:肿瘤再生17例(44%)。10例患者(26%)在随访期间需要额外治疗。结论:本研究提示听神经瘤的不完全切除与肿瘤复发的显著风险相关,需要后续干预。
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Recurrence of acoustic neuroma after incomplete resection.

Objective: To determine the risk of recurrent tumor in patients after incomplete resection of acoustic neuroma.

Study design: Retrospective case review.

Setting: A tertiary referral center.

Patients: Thirty-nine patients were identified who underwent incomplete resection of acoustic neuroma between January 1988 and December 1993, and had a minimum follow-up of 3.5 years, at a mean of 6.2 years (range 3.5-10.2 years).

Intervention: Regular follow-up. using either computed axial tomography or magnetic resonance imaging yearly.

Main outcome measures: Growth of residual tumor as determined by the increase in its greatest dimension on follow-up imaging studies and the necessity for additional treatment.

Results: Tumor regrowth occurred in 17 patients (44%). Ten patients (26%) required additional treatment during the follow-up period.

Conclusion: This study suggests that incomplete resection of acoustic neuroma is associated with a significant risk of recurrent tumor requiring subsequent intervention.

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