C.Oliver Wong MD, PhD, FACP, FACNP , Alfonso N. Pham MD , Howard J. Dworkin MD, FACP, FACNP
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F-18 FDG Accumulation in an Octreotide Negative Merkel Cell Tumor
Regional positron emission tomography (PET) imaging with F-18 Fluorodeoxyglucose (FDG) was performed in a patient with pathologically proven Merkel cell tumor around the right knee region. Prior to the PET imaging, whole-body Indium-111 octreotide scan was performed in this patient but was negative. F-18 FDG was offered as an attempt to image this somatostatin-receptor negative Merkel cell tumor. The PET images delineate a series of focal abnormal uptake along the right lower extremity without evidence of distant metastasis. Patient was treated locally. The positive accumulation of F-18 FDG in Merkel cells may offer a tool for defining the extent of this rare neuroendocrine tumor.
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