诊断中的抗体——从免疫测定到蛋白质芯片

Carl A.K Borrebaeck
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引用次数: 302

摘要

抗体被广泛用作各种不同分析的诊断工具。单克隆和重组抗体提供了永无止境的分子来源,可以为新的遗传结构产生无限的可能性。抗体仍然非常流行,现在也被用于使用蛋白质芯片对蛋白质组进行微阵列分析。本文回顾了抗体作为诊断工具的最新机遇。
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Antibodies in diagnostics – from immunoassays to protein chips

Antibodies are used extensively as diagnostic tools in a wide array of different analyses. Monoclonal and recombinant antibodies provide a never ending source of molecules and can produce endless possibilities for novel genetic constructs. Antibodies are still very much in vogue and are now also being used in microarray analysis of the proteome using protein chips. Here, recent opportunities presented by antibodies as diagnostic tools are reviewed.

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