{"title":"炎症和免疫中的趋化因子","authors":"Marco Baggiolini, Pius Loetscher","doi":"10.1016/S0167-5699(00)01672-8","DOIUrl":null,"url":null,"abstract":"<div><p>Since the discovery of interleukin 8 (IL-8), about 50 chemokines have been characterized. Originally, they were considered as inducible mediators of inflammation, but in recent years, several chemokines have been identified that are expressed constitutively and function in the physiological traffic and homing of leukocytes.</p></div>","PeriodicalId":73346,"journal":{"name":"Immunology today","volume":"21 9","pages":"Pages 418-420"},"PeriodicalIF":0.0000,"publicationDate":"2000-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0167-5699(00)01672-8","citationCount":"252","resultStr":"{\"title\":\"Chemokines in inflammation and immunity\",\"authors\":\"Marco Baggiolini, Pius Loetscher\",\"doi\":\"10.1016/S0167-5699(00)01672-8\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Since the discovery of interleukin 8 (IL-8), about 50 chemokines have been characterized. Originally, they were considered as inducible mediators of inflammation, but in recent years, several chemokines have been identified that are expressed constitutively and function in the physiological traffic and homing of leukocytes.</p></div>\",\"PeriodicalId\":73346,\"journal\":{\"name\":\"Immunology today\",\"volume\":\"21 9\",\"pages\":\"Pages 418-420\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2000-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/S0167-5699(00)01672-8\",\"citationCount\":\"252\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Immunology today\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0167569900016728\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Immunology today","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0167569900016728","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Since the discovery of interleukin 8 (IL-8), about 50 chemokines have been characterized. Originally, they were considered as inducible mediators of inflammation, but in recent years, several chemokines have been identified that are expressed constitutively and function in the physiological traffic and homing of leukocytes.
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