全基因组退化重复序列的计算与可视化。

S Kurtz, E Ohlebusch, C Schleiermacher, J Stoye, R Giegerich
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引用次数: 0

摘要

基因组DNA的重复结构蕴藏着许多有待发现的秘密。在基因组或基因组间尺度上对重复DNA的系统研究需要广泛的算法支持。本文所述的repter系列程序旨在作为此类研究的基本工具。提供了各种类型重复序列的高效和完整的检测,以及显著性评估,交互式可视化和与其他分析程序的简单接口。
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Computation and visualization of degenerate repeats in complete genomes.

The repetitive structure of genomic DNA holds many secrets to be discovered. A systematic study of repetitive DNA on a genomic or inter-genomic scale requires extensive algorithmic support. The REPuter family of programs described herein was designed to serve as a fundamental tool in such studies. Efficient and complete detection of various types of repeats is provided together with an evaluation of significance, interactive visualization, and simple interfacing to other analysis programs.

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