人类和小鼠RAMP基因的基因组结构和染色体定位。

C Derst, H Engel, K Grzeschik, J Daut
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引用次数: 14

摘要

分离得到了人、鼠受体活性修饰蛋白和相关小鼠降钙素受体样受体的cdna。人类RAMP1和RAMP3基因具有2个内含子,人类RAMP2基因具有3个内含子。人类RAMP1被分配到染色体2q36- >q37.1, RAMP2被分配到17q12- >q21.1, RAMP3被分配到7p13- >p12。小鼠Ramp1被分配到1号染色体,Ramp2和Ramp3被分配到11号染色体。
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Genomic structure and chromosome mapping of human and mouse RAMP genes.

The cDNAs for human and murine Receptor Activity Modifying Proteins and for the associated murine Calcitonin Receptor Like Receptor were isolated. The human RAMP1 and RAMP3 genes possess two introns and human RAMP2 possesses three introns. Human RAMP1 was assigned to chromosome 2q36-->q37.1, RAMP2 to 17q12-->q21.1 and RAMP3 to 7p13-->p12. Mouse Ramp1 was assigned to chromosome 1 and Ramp2 and Ramp3 were assigned to chromosome 11.

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