人类染色体2q31- >q32.1区域2个脆弱位点和7个同源盒基因的聚类。

Cytogenetics and cell genetics Pub Date : 2000-01-01 DOI:10.1159/000015651

M Z Limongi, F Pelliccia, L Gaddini, A Rocchi

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引用次数: 6

摘要

在本研究中，我们使用FISH检测了位于2号染色体q31区域的一组同源盒基因，即DLX1/DLX2、EVX2和4个HOXD基因(10,11,12,13)与位于2q31和2q32.1的FRA2G和FRA2H脆弱位点之间的关系。我们的研究结果表明，这些同源盒基因位于两个脆弱区域之间。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Clustering of two fragile sites and seven homeobox genes in human chromosome region 2q31-->q32.1.

In this study we have used FISH to examine the relationship between a group of homeobox genes, namely DLX1/DLX2, EVX2 and four HOXD genes (10, 11, 12, 13), that map to region q31 on chromosome 2, and the FRA2G and FRA2H fragile sites located at 2q31 and 2q32.1 respectively. Our results indicate that these homeobox genes lie between the two fragile regions.

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Cytogenetics and cell genetics

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