【门诊感染的诊断与抗生素治疗】。

M S Stürchler, P Vuille, E Zemp, P Tschudi, W Zimmerli
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引用次数: 0

摘要

背景:这项研究的目的是根据现行准则和产生耐药性的问题,分析选定传染病的诊断和治疗方法,特别是抗生素的使用。方法:向瑞士巴塞尔城市州和巴塞尔州的所有内科或全科医生发送问卷。结果:440名医生中,286名(65%)参加了研究。最常见的感染诊断是膀胱炎(16.6%)、流感样综合征(16.4%)、急性支气管炎(12.3%)和扁桃体咽炎(10.1%)。抗菌药物治疗最常见的适应症是膀胱炎(19.9%)、急性鼻窦炎(14.1%)、急性支气管炎(11.5%)和扁桃体咽炎(9.2%)。大环内酯类(24.0%)、氨基霉素类(22.6%)和氟喹诺酮类(16.8%)是最常开的抗生素。结论:绝大多数医师的诊断和治疗遵循理性原则。然而,也发现了一些例外,例如,肺炎诊断时遗漏x线(24%),病毒性疾病治疗中使用抗生素,以及扁桃体咽炎的抗生素治疗,尽管对a组链球菌的快速抗原检测试验呈阴性(75%)。
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[Diagnosis and antibiotic therapy of infections in outpatients].

Background: The study aim was to analyse the diagnostic and therapeutic approach to selected infectious diseases, in particular with regard to the use of antibiotics, in the light of current guidelines and the problem of developing resistance.

Methods: A questionnaire was sent to all physicians with a general or internal medicine practice in the Cantons Basel-Stadt and Basel-Landschaft, Switzerland.

Results: Of 440 physicians, 286 (65%) took part in the study. The most frequent diagnoses of infection were cystitis (16.6%), flu-like syndrome (16.4%), acute bronchitis (12.3%), and tonsillopharyngitis (10.1%). The most frequent indications for antimicrobial therapy were cystitis (19.9%), acute sinusitis (14.1%), acute bronchitis (11.5%), and tonsillopharyngitis (9.2%). Macrolides (24.0%), aminopenicillins (22.6%), and fluoroquinolones (16.8%) were the most frequently prescribed antibiotics.

Conclusions: The majority of physicians diagnosed and treated according to rational principles. However, a few exceptions were found, e.g. omission of x-ray in the diagnosis of pneumonia (24%), the use of antibiotics in the treatment of viral diseases and antibiotic therapy for tonsillopharyngitis despite a negative rapid antigen detection test against group A streptococci (75%).

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