Dale I. Godfrey , Kirsten J.L. Hammond , Lynn D. Poulton , Mark J. Smyth , Alan G. Baxter
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引用次数: 959
摘要
NK1.1+ T (NKT)细胞在免疫应答中的作用范围从抑制自身免疫到肿瘤排斥。这些细胞的异质性导致了围绕其发育和功能的争议。本综述旨在提供NKT细胞生物学的最新进展,并尽可能比较已知的NKT细胞亚群。
The proposed roles of NK1.1+ T (NKT) cells in immune responses range from suppression of autoimmunity to tumor rejection. Heterogeneity of these cells contributes to the controversy surrounding their development and function. This review aims to provide an update on NKT cell biology and, whenever possible, to compare what is known about NKT-cell subsets.