椎体功能不全:何时干预,如何干预?

Jenkins, White, Ramee, Collins, McKinley
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摘要

经皮腔内血管成形术和支架置入术治疗主动脉上动脉粥样硬化性血管阻塞在无名动脉、锁骨下动脉和颈动脉中变得相对常见。然而,经皮椎动脉粥样硬化性疾病的血运重建术是一种不常用的治疗选择。我们认为后循环、症状性椎基底动脉粥样硬化性疾病的血管成形术和支架置入术是一种安全有效的方法,可以避免大手术相关的并发症。由于手术成功率有限和手术发病率增加,有症状的椎动脉狭窄很少进行手术重建术。球囊血管成形术单独或联合支架植入与高成功率和低再狭窄率相关,尽管缺乏已发表的同行评审数据。椎动脉血管内支架单独放置治疗后循环缺血的系列研究尚未发表。典型的后循环(椎基底动脉)缺血性症状包括复视、头晕、跌落发作、步态障碍或短暂性脑缺血发作。最初的治疗是抗凝或抗血小板治疗。我们认为初级支架置入术是椎动脉血管重建术的治疗选择,因为其技术成功率高,发病率和死亡率低,并且长期耐用。
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Vertebral Insufficiency: When to Intervene and How?

Percutaneous transluminal angioplasty and stenting of supra-aortic atherosclerotic vascular obstructions is becoming relatively common in the innominate, subclavian, and carotid arteries. However, percutaneous revascularization of atherosclerotic vertebral artery disease is an infrequently used treatment option. We believe that angioplasty and stent placement of posterior circulation, symptomatic, vertebrobasilar atherosclerotic disease is a safe and effective approach which avoids the morbidity associated with major surgery. Surgical revascularization of symptomatic vertebral artery stenosis is rarely performed due to limited surgical success and increased surgical morbidity. Balloon angioplasty alone or combined with stenting is associated with high success rates and low restenosis rates, although there is a scarcity of published peer-reviewed data. Series of endovascular stent placement in vertebral arteries alone for the treatment of posterior circulation ischemia is unpublished.Typical posterior circulation (vertebrobasilar) ischemic symptoms include diplopia, dizziness, drop attack, gait disturbance, or a transient ischemic attack. Initial treatment is with anticoagulation or antiplatelet therapy. We believe primary stent placement is the treatment of choice for vertebral artery revascularization due to the high technical success rate, low incidence of morbidity and mortality, and long-term durability.

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