结构基因组学中的整合数据库分析。

M Gerstein
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引用次数: 63

摘要

结构基因组学的一个重要方面是将坐标数据与与系统发育发生、蛋白质功能、基因表达和蛋白质-蛋白质相互作用相关的全基因组信息联系起来。综合数据库分析允许人们从多个角度调查蛋白质折叠的“有限部分列表”,突出某些褶皱和结构特征,以特定的方式突出。
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Integrative database analysis in structural genomics.

An important aspect of structural genomics is connecting coordinate data with whole-genome information related to phylogenetic occurrence, protein function, gene expression, and protein-protein interactions. Integrative database analysis allows one to survey the 'finite parts list' of protein folds from many perspectives, highlighting certain folds and structural features that stand out in particular ways.

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Hardware and software Structural aspects of protein synthesis Starting off right Incorporation of aminoacyl-tRNA into the ribosome as seen by cryo-electron microscopy Protein structure modeling for structural genomics.
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