[Treatment of multiple myeloma].

The chief advances observed over the last 15 years in the treatment of multiple myeloma arise from intensive procedures and in particular autologous bone marrow transplantation. However, even if autologous bone marrow transplantation increases the rate of total remissions, no plateau is yet observable in the survival curve and transplantation is probably not a curative therapy. Hopes for the future seem to rest on intensive chemotherapy combined with innovative therapeutic approaches such as diphosphonates, thalidomide or immunotherapy.