真菌毒素方法综述、现状及未来需求。

J Gilbert
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引用次数: 48

摘要

本文回顾了食品中真菌毒素分析的当前要求,并确定了推动新方法开发和验证的立法和其他因素。真菌毒素的新法规限制和实验室仅使用经过验证的方法的分析质量保证要求被视为推动发展的主要因素。确定了三种主要的方法,它们服务于不同的目的,可分为筛选,官方和研究。对每一种情况的现状和未来需要都进行了评估。除了对分析方法趋势的概述外,还确定了分析质量保证的其他一些领域,如参与能力测试和参考材料。
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Overview of mycotoxin methods, present status and future needs.

This article reviews current requirements for the analysis for mycotoxins in foods and identifies legislative as well as other factors that are driving development and validation of new methods. New regulatory limits for mycotoxins and analytical quality assurance requirements for laboratories to only use validated methods are seen as major factors driving developments. Three major classes of methods are identified which serve different purposes and can be categorized as screening, official and research. In each case the present status and future needs are assessed. In addition to an overview of trends in analytical methods, some other areas of analytical quality assurance such as participation in proficiency testing and reference materials are identified.

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Erratum: Alfonso D, Johnson HA, Colman-Saizarbitoria T, Presley CP, McCabe GP, McLaughlin JL (1996): SARs of annonaceous acetogenins in rat liver mitochondria. Nat Toxins 4:181-188. Advances in detection methods for fungal and algal toxins. HPLC/MS analysis of fusarium mycotoxins, fumonisins and deoxynivalenol. Neuronal binding of tetanus toxin compared to its ganglioside binding fragment (H(c)). A new type sandwich immunoassay for microcystin: production of monoclonal antibodies specific to the immune complex formed by microcystin and an anti-microcystin monoclonal antibody.
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