[GABA和吡乙胺对实验性运动不足时线粒体ADP磷酸化的影响]。

Voprosy meditsinskoi khimii Pub Date : 2002-09-01
O P Sotskiĭ, V P Akopian, L G Zhamgarian, A G Zhamgarian
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引用次数: 0

摘要

雄性大鼠长期运动受限,肝脏和心脏线粒体ADP磷酸化受损。在15天和45天后观察到最显著的变化。对运动能力低下的动物给予GABA和吡乙胺诱导ADP磷酸化过程“正常化”的趋势。
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[Effect of GABA and pyracetam on mitochondrial ADP phosphorylation in experimental hypokinesia].

Long-term limitation of motor activity of male rats is accompanied by impairments of mitochondrial ADP phosphorylation in liver and heart. The most significant changes were observed after 15 and 45 days of hypokinesia. Administration of GABA and pyracetam to animals subjected to hypokinesia induced a tendency to "normalization" of ADP phosphorilation processes.

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