100例前庭神经鞘瘤手术结果分析。

IF 0.2 4区 医学 Q3 Medicine B-Ent Pub Date : 2003-01-01
Th Somers, F E Offeciers, I Schatteman
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引用次数: 0

摘要

1991年至2000年间,安特卫普圣奥古斯丁医院大学门诊科共发现154例脑桥小脑角(CPA)肿瘤。其中,经核磁共振发现的前庭神经鞘瘤127例。值得注意的是,其中5%的ABR延迟在正常范围内。100例患者通过迷路入路(66例)或乙状结肠后入路(34例)行肿瘤切除,所有患者随访至少2年。对于较大的肿瘤(CPA扩展> 2cm)或听力差的患者采用经迷路入路。对于CPA肿瘤扩展小于2 cm且患侧残余听力可用的患者(至少< 50 dB PTA, > 50% SSD),采用乙状结肠后入路并内镜控制。大多数患者(96%)术前面部功能为House-Brackmann 1级或2级。虽然这一群体在术后6个月降至76%,但在2年内再次上升至84%。因此,88%术前面部功能正常的患者在两年后达到I级或II级。面部的结果很大程度上取决于肿瘤的大小。对于小肿瘤(CPA延伸小于10 mm)有良好的结果(House-Brackmann 1级或2级)(92%),对于中等肿瘤(11-25 mm)仍然有良好的结果(82%),但对于大肿瘤(> 26 mm)不太明显(56%)。在乙状结肠后干预中,38%的患者有可能保留听力。虽然不平衡和头痛是术后早期比较常见的症状(分别为52%和31%),但这些症状随着时间的推移而减少,两年后不常见(不平衡= 7%,头痛= 4%)。我们的结果与三个大型多中心研究进行了比较。它们与文献中的数据一致,并且与更好的结果相比较有利。尽管存在良好的面神经和听力评分系统,但作者遗憾的是,对肿瘤大小的测量仍未达成普遍共识。这将有助于不同中心之间的数据比较和治疗方式之间的选择。
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Results of 100 vestibular schwannoma operations.

Between 1991 and 2000, 154 cerebello-pontine angle (CPA) tumors were seen at the University ENT-department of the Sint-Augustinus Hospital, Antwerp. Amongst these, 127 were vestibular schwannomas detected by MR-imaging. Noteworthy is that in 5% of these, the ABR latencies were within normal limits. One hundred patients underwent tumor removal either by the translabyrinthine (66) or by the retrosigmoid (34) approach and all had a follow-up of at least two years. For large tumors (> 2 cm extension in the CPA) or in the case of poor hearing the translabyrinthine approach was used. For patients with tumor extension in the CPA ofless than 2 cm and with serviceable residual hearing on the affected side, (at least < 50 dB PTA, > 50% SSD) the retrosigmoid approach with endoscopic control was used. Most patients (96%) had a House-Brackmann grade 1 or 2 facial function before surgery. Although this group dropped to 76% 6 months after surgery it increased again to reach 84% within 2 years. Thus, 88% percent of patients with normal preoperative facial function achieved a Grade I or II after two years. The facial outcome is very much dependent on the size of the tumor. A good result (House-Brackmann Grade 1 or 2) is the rule (92%) for small tumors (< 10 mm extension in the CPA), still attainable (82%) for medium tumors (11-25 mm), but less apparent (56%) for large tumors (> 26 mm). It was possible to preserve hearing in 38% of the retrosigmoid interventions. Although unbalance and headache are rather frequent early postoperative symptoms (respectively 52% and 31%), these complaints decrease with time and are infrequent after two years (unbalance = 7%, headache = 4%). Our results were compared with three large multicentric studies. They are in line with data from the literature and compare favorably with the better results. Although good grading systems exist for facial nerve and hearing outcomes, the authors regret that a general consensus on tumor size measurement is still not yet available. It would facilitate data comparison between different centers and the choice between the therapeutical modalities.

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来源期刊
B-Ent
B-Ent 医学-耳鼻喉科学
CiteScore
0.60
自引率
0.00%
发文量
2
审稿时长
6-12 weeks
期刊介绍: Throughout its history, the Royal Belgian Society of Oto-rhino-laryngology, Head and Neck Surgery, the home society of B-ENT, aims to disseminate both the scientific and the clinical knowledge of otorhinolaryngology field primarily in Belgium and its regions. In accordance with this aim, publishing a scientific journal has become the number one objective of the Society. Accordingly, B-ENT contributes to the scientific memory of Belgium considering its deep-rooted history.
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