K Hirota, R Hattori, H Sajiki, Y Monguchi, O Muraoka, G Tanabe
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Synthesis of 2,3-dihydroinosine derivatives by reduction using BH3-THF.
A novel reductive method for the chemical modification of nucleosides is described. Reaction of inosine derivatives with boran-THF resulted in the regioselective reduction of purine ring to afford the corresponding 2,3-dihydroinosine derivatives in moderate yields.
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