DNA双链形成的新的热力学表征和过渡机制。

P Wu, N Sugimoto
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引用次数: 1

摘要

提出了一种新的DNA双链结合过渡机制,并进一步推导了分离过渡模型。不同摩尔比下的实验结果表明,双链结合转变是不完美的,单链的热力学性质和自转变行为对DNA双链的形成有显著影响。
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New thermodynamic characterization and transition mechanism of DNA duplex formation.

A new transition mechanism of DNA duplex association was proposed and a segregated transition model (STM) was further derived. The experimental results in various molar ratios showed that the duplex association transition is imperfect and the thermodynamic properties and self-transition behavior of single strands exert a significant influence on DNA duplex formation.

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