Andrei P Sommer, Uri Oron, Anne-Marié Pretorius, David S McKay, Neva Ciftcioglu, Adam R Mester, E Olavi Kajander, Harry T Whelan
{"title":"纳米细菌的光调制复制与心脏病的初步研究。","authors":"Andrei P Sommer, Uri Oron, Anne-Marié Pretorius, David S McKay, Neva Ciftcioglu, Adam R Mester, E Olavi Kajander, Harry T Whelan","doi":"10.1089/104454703768247819","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>The purpose of this preliminary study is to evaluate the effect of various wavelengths of light on nanobacteria (NB).</p><p><strong>Background data: </strong>NB and mitochondria use light for biological processes. NB have been described as multifunctional primordial nanovesicles with the potential to utilize solar energy for replication. NB produce slime, a process common to living bacteria. Slime release is an evolutionary important stress-dependent phenomenon increasing the survival chance of individual bacteria in a colony. In the cardiovascular system, stress-induced bacterial colony formation may lead to a deposition of plaque.</p><p><strong>Methods: </strong>Cultured NB were irradiated with NASA-LEDs at different wavelengths of light: 670, 728 and 880 nm. Light intensities were about 500k Wm(-2), and energy density was 1 x 10(4) J m(-2).</p><p><strong>Results: </strong>Monochromatic light clearly affected replication of NB. Maximum replication was achieved at 670 nm.</p><p><strong>Conclusions: </strong>The results indicate that suitable wavelengths of light could be instrumental in elevating the vitality level of NB, preventing the production of NB-mediated slime, and simultaneously increasing the vitality level of mitochondria. The finding could stimulate the design of cooperative therapy concepts that could reduce death caused by myocardial infarcts.</p>","PeriodicalId":79503,"journal":{"name":"Journal of clinical laser medicine & surgery","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2003-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1089/104454703768247819","citationCount":"16","resultStr":"{\"title\":\"A preliminary investigation into light-modulated replication of nanobacteria and heart disease.\",\"authors\":\"Andrei P Sommer, Uri Oron, Anne-Marié Pretorius, David S McKay, Neva Ciftcioglu, Adam R Mester, E Olavi Kajander, Harry T Whelan\",\"doi\":\"10.1089/104454703768247819\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>The purpose of this preliminary study is to evaluate the effect of various wavelengths of light on nanobacteria (NB).</p><p><strong>Background data: </strong>NB and mitochondria use light for biological processes. NB have been described as multifunctional primordial nanovesicles with the potential to utilize solar energy for replication. NB produce slime, a process common to living bacteria. Slime release is an evolutionary important stress-dependent phenomenon increasing the survival chance of individual bacteria in a colony. In the cardiovascular system, stress-induced bacterial colony formation may lead to a deposition of plaque.</p><p><strong>Methods: </strong>Cultured NB were irradiated with NASA-LEDs at different wavelengths of light: 670, 728 and 880 nm. Light intensities were about 500k Wm(-2), and energy density was 1 x 10(4) J m(-2).</p><p><strong>Results: </strong>Monochromatic light clearly affected replication of NB. Maximum replication was achieved at 670 nm.</p><p><strong>Conclusions: </strong>The results indicate that suitable wavelengths of light could be instrumental in elevating the vitality level of NB, preventing the production of NB-mediated slime, and simultaneously increasing the vitality level of mitochondria. The finding could stimulate the design of cooperative therapy concepts that could reduce death caused by myocardial infarcts.</p>\",\"PeriodicalId\":79503,\"journal\":{\"name\":\"Journal of clinical laser medicine & surgery\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2003-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1089/104454703768247819\",\"citationCount\":\"16\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of clinical laser medicine & surgery\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1089/104454703768247819\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of clinical laser medicine & surgery","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1089/104454703768247819","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
A preliminary investigation into light-modulated replication of nanobacteria and heart disease.
Objective: The purpose of this preliminary study is to evaluate the effect of various wavelengths of light on nanobacteria (NB).
Background data: NB and mitochondria use light for biological processes. NB have been described as multifunctional primordial nanovesicles with the potential to utilize solar energy for replication. NB produce slime, a process common to living bacteria. Slime release is an evolutionary important stress-dependent phenomenon increasing the survival chance of individual bacteria in a colony. In the cardiovascular system, stress-induced bacterial colony formation may lead to a deposition of plaque.
Methods: Cultured NB were irradiated with NASA-LEDs at different wavelengths of light: 670, 728 and 880 nm. Light intensities were about 500k Wm(-2), and energy density was 1 x 10(4) J m(-2).
Results: Monochromatic light clearly affected replication of NB. Maximum replication was achieved at 670 nm.
Conclusions: The results indicate that suitable wavelengths of light could be instrumental in elevating the vitality level of NB, preventing the production of NB-mediated slime, and simultaneously increasing the vitality level of mitochondria. The finding could stimulate the design of cooperative therapy concepts that could reduce death caused by myocardial infarcts.