正常人转铁蛋白的分离

Jan-Olof Jeppsson, John Sjöquist
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引用次数: 5

摘要

乙醇分馏的人转铁蛋白(转铁蛋白CC)在阴离子交换纤维素(cm -纤维素)上进行色谱分离时可分为两部分。这两种组分在免疫学、生物学和物理性质上具有相似性。它们在碳水化合物组成上存在一些差异。如果来自个体供者的全血清采用相同的色谱程序,则发现转铁蛋白的分离模式相同。
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Separation of normal human transferrin into two fractions

Ethanol-fractionated human transferrin (transferrin CC) separates into two fractions when subjected to chromatography on anion-exchange cellulose (CM-cellulose). The two fractions show similarities in their immunological, biological and physical properties. Some differences in their carbohydrate composition are demonstrated.

The same separation pattern of transferrin is found if whole serum from individual donors is subjected to the same chromatographic procedure.

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