GaAs激光辅助治疗指屈肌腱康复效果的研究。

Neslihan Ozkan, Lale Altan, Umit Bingöl, Selçuk Akln, Merih Yurtkuran
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引用次数: 29

摘要

目的:采用安慰剂对照双盲前瞻性研究模型,探讨激光光刺激对人指屈肌腱康复的影响。背景资料:低能量激光治疗已应用于几种类风湿和软组织疾病,成功率不同,在动物实验中也显示出对肌腱愈合有积极作用,但迄今为止尚无关于激光光刺激治疗人类肌腱的临床研究报道。材料和方法:本研究共对25例5个解剖区41例指屈肌腱损伤患者进行了研究。第一组(13例21位),漩涡和红外GaAs二极管激光,频率为100hz。于术后第8天至第21天应用,所有患者均给予华盛顿康复计划,直至第12周结束。在第二组(12例患者中有20个手指),给予相同的治疗方案,但在应用过程中关闭激光仪器。结果:研究结果显示,激光治疗组仅在水肿减轻参数上有显著改善(p < 0.01),但在疼痛减轻、手部握力以及根据Strickland和buckgramcko系统采用总主动运动和指尖到手掌远端折痕距离参数进行的功能评估方面,两组差异无显著性(p > 0.05)。结论:在我们的研究中,补充GaAs激光应用后立即和12周内水肿减少的显著改善被解释为对人类屈肌腱损伤康复的重要贡献,因为已知水肿在肌腱愈合的早期和晚期对功能恢复有不利影响。然而,我们的研究未能显示补充GaAs激光应用对人体屈肌腱损伤康复的其他功能恢复参数的显着积极作用,我们建议使用不同的激光类型和剂量对该主题进行进一步的临床研究,以描述这种有前景的治疗方式的作用。
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Investigation of the supplementary effect of GaAs laser therapy on the rehabilitation of human digital flexor tendons.

Objective: To investigate the effect of laser photostimulation in rehabilitation of human digital flexor tendons with a placebo-controlled double-blind prospective study model.

Background data: Low-energy laser therapy has been applied in several rheumatoid and soft tissue disorders with a varying rate of success and it has also been shown to have a positive effect on tendon healing in animal experiments, but no clinical study on laser photostimulation in the treatment of human tendons has been reported to date.

Materials and methods: This study was performed in a total of 25 patients with 41 digital flexor tendon injuries in five anatomical zones. In Group I (21 digits in 13 patients), whirlpool and infrared GaAs diode laser with a frequency of 100 Hz. was applied between the 8th and 21st days postoperatively and all patients were given the Washington rehabilitation program until the end of the 12th week. In Group II (20 digits in 12 patients), the same treatment protocol was given but the laser instrument was switched off during applications.

Results: The results of the study showed a significant improvement in the laser-treated group only for the parameter of edema reduction (p < 0.01) but the difference between the two groups was non-significant for pain reduction, hand grip strength, and functional evaluation performed according to Strickland and Buck-Gramcko systems using total active motion and fingertip-to distal palmar crease distance parameters (p > 0.05).

Conclusions: Significant improvement obtained in edema reduction both immediately and 12 weeks after supplementary GaAs laser application in our study has been interpreted as an important contribution to the rehabilitation of human flexor tendon injuries because edema is known to have a detrimental effect on functional recovery during both early and late stages of tendon healing. However, our study has failed to show a significant positive effect of supplementary GaAs laser application on the other functional recovery parameters of human flexor tendon injury rehabilitation and we suggest further clinical study in this topic be done using different laser types and dosages in order to delineate the role of this promising treatment modality.

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Optimal dye concentration and irradiance for laser-assisted vascular anastomosis. Cleaning of the root canal using Nd:YAP laser and its effect on the mineral content of the dentin. Evaluation of trans-scleral diode laser using diopexy probe for subfoveal choroidal neovascular membrane in age-related macular degeneration. Safety parameters for pulp temperature during selective ablation of caries by KTP laser in vitro. Investigation of the supplementary effect of GaAs laser therapy on the rehabilitation of human digital flexor tendons.
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