Denton A. Cooley, Alexander Romagnoli, John D. Milam, Mattie I. Bossart
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A method of preparing woven Dacron aortic grafts to prevent interstitial hemorrhage.
Severe and even fatal hemorrhage may be caused by bleeding through the interstices of a fabric graft. Improved fabrication of grafts with appropriate porosity for the conditions encountered has provided better hemostasis. Yet in some situations, bleeding through the fabric still presents a problem. A method of preclotting with autologous platelet rich plasma (PRP) and autoclaving is described. Gross and microscopic studies along with clinical applications confirm the effectiveness of the technique.
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