{"title":"抗叶酸药——过去、现在和未来。","authors":"Aleem Gangjee, Hiteshkumar D Jain","doi":"10.2174/1568011043352803","DOIUrl":null,"url":null,"abstract":"<p><p>This short perspective briefly covers selected aspects of the past, present and future of antifolates in chemotherapy. Both classical and nonclassical analogs currently in the preclinical stage and clinically used agents are covered.</p>","PeriodicalId":10914,"journal":{"name":"Current medicinal chemistry. Anti-cancer agents","volume":"4 5","pages":"405-10"},"PeriodicalIF":0.0000,"publicationDate":"2004-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"8","resultStr":"{\"title\":\"Antifolates -- past, present and future.\",\"authors\":\"Aleem Gangjee, Hiteshkumar D Jain\",\"doi\":\"10.2174/1568011043352803\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>This short perspective briefly covers selected aspects of the past, present and future of antifolates in chemotherapy. Both classical and nonclassical analogs currently in the preclinical stage and clinically used agents are covered.</p>\",\"PeriodicalId\":10914,\"journal\":{\"name\":\"Current medicinal chemistry. Anti-cancer agents\",\"volume\":\"4 5\",\"pages\":\"405-10\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2004-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"8\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Current medicinal chemistry. Anti-cancer agents\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.2174/1568011043352803\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current medicinal chemistry. Anti-cancer agents","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2174/1568011043352803","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
This short perspective briefly covers selected aspects of the past, present and future of antifolates in chemotherapy. Both classical and nonclassical analogs currently in the preclinical stage and clinically used agents are covered.