[冠状动脉手术的风险评估:使用EuroSCORE的单中心经验]。

Isidoro Di Bella, Uberto Da Col, Francesco Del Sindaco, Stefano Pasquino, Alessandro Affronti, Antonella Santucci, Temistocle Ragni
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引用次数: 0

摘要

背景:在心脏外科手术中最常用的风险分层系统之一是EuroSCORE。它考虑了一些可能影响手术风险的危险因素。本研究的目的是评估我们的结果是否与孤立冠状动脉搭桥手术有关,该系统是否可以很好地预测,哪些参数对医院死亡率具有统计学意义。方法:2002年1月1日至2004年4月30日,对724例患者行离体心肌血运重建术。分析用于EuroSCORE系统评价的所有危险因素以及EuroSCORE值本身,以评估其对预测手术风险的意义。定量变量采用Student’st检验,分类变量采用列联表中的chi2进行单因素统计分析。多因素分析采用Logistic回归。结果:累计手术死亡率为3.7%(27例)。EuroSCORE值、年龄、术前危急状态、急诊和低射血分数均为住院死亡率的有统计学意义的危险因素。多变量分析只排除了临界术前状态。意外表分析显示,75岁以上患者手术风险有统计学意义。同样的分析显示,三组的死亡率在统计学上存在差异,并且表明该系统可能高估较低EuroSCOREs的死亡率,而低估较高EuroSCOREs的死亡率。结论:本研究证实了EuroSCORE在这组患者中风险分层的价值。计算中考虑的最重要参数证实了它们的预测价值。这种模式可以对我们的手术实践进行可靠的质量控制。
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[Risk evaluation in coronary surgery: a single center experience using the EuroSCORE].

Background: One of the most utilized systems for risk stratification in cardiac surgery is the EuroSCORE. It considers some risk factors that should influence the surgical risk. The aim of this study was to evaluate if our results, related to isolated coronary artery bypass surgery, are well predictable by this system and which are the parameters statistically significant for hospital mortality.

Methods: From January 1, 2002 to April 30, 2004, 724 patients underwent isolated myocardial revascularization. All risk factors considered for the EuroSCORE system evaluation and the EuroSCORE value itself were analyzed to assess their significance to predict surgical risk. Univariate statistical analysis was performed with the Student's t-test for quantitative variables and the chi2 in contingency tables for categorical variables. Logistic regression was used for multivariate analysis.

Results: Cumulative operative mortality was 3.7% (27 patients). The EuroSCORE value, age, critical preoperative state, emergency and low ejection fraction were all statistically significant risk factors for hospital mortality. Multivariate analysis excluded only the critical preoperative state. The analysis of contingency tables showed that the surgical risk was statistically significant above the age of 75 years. The same analysis revealed that the mortality rate was statistically different in the three groups and it showed that the system could over-estimate mortality at lower EuroSCOREs and under-estimate mortality at higher EuroSCOREs.

Conclusions: This study confirms the value of the EuroSCORE for risk stratification in this group of patients. The most important parameters considered for its calculation confirmed their predictive value. This model allows a reliable quality control of our surgical practice.

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[Italian national register of major coronary events: attack rates and fatality in different areas of the country]. [Angiotensin-converting enzyme inhibition and cardiovascular prevention: more than twenty years of clinical success]. [Atrial fibrillation and cardioversion: role of transesophageal echocardiography]. [Economic impact of cardiac resynchronization therapy in patients with heart failure. Available evidence and evaluation of the CRT-Eucomed model for analysis of cost-effectiveness]. [Impact of reperfusion strategies on in-hospital outcome in ST-elevation myocardial infarction in a context of interhospital network: data from the prospective VENERE registry (VENEto acute myocardial infarction REgistry].
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