1993-2000年伊朗马什哈德急性中毒模式。

R Afshari, R Majdzadeh, M Balali-Mood
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引用次数: 158

摘要

在伊朗,毒品和化学药品几乎很容易买到。天然毒素,如有毒植物和动物,也存在于该国大部分地区。因此,急性中毒,无论是故意的还是意外的,以及药物滥用/成瘾在伊朗很常见。尽管有这些困难,但在这个国家没有毒物控制和监测中心来收集信息和分析数据。对1993年3月21日至2000年3月20日在马什哈德伊玛目礼萨(p)大学医院转诊的所有中毒患者中系统随机抽取的10%的档案(71589例)进行回顾性筛查。年轻人(40.3%)和学龄儿童(22.9%)是最脆弱的群体。平均年龄22.3岁(标准差14.38),最小小于1岁,最大为98岁。女性占优势(53.4%)。故意中毒(54.4%)比意外暴露(45.2%)更为常见。刑事投毒案件14起。79.7%的暴露是通过摄入,其次是皮肤暴露(14.1%)和吸入(6.2%)。大多数患者(83.7%)来自城市地区。大多数患者(68.6%)在急诊毒理学诊所治疗后出院,19.2%暂时住院,11.3%住院24小时。毒物的主要类别为药品(61.4%)、化学品(22.8%)和天然毒素(16.6%)。中毒总人数以春季和夏季较高(62.8%)。总之,急性中毒,特别是自我中毒,在伊朗很常见。由于该国没有常规提供医疗文件,因此这项回顾性研究的结果可用于监测。在地方卫生系统内建立流畅的数据收集和分析是未来的挑战。
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Pattern of acute poisonings in Mashhad, Iran 1993-2000.
Drugs and chemicals are almost easily available in Iran. Natural toxins as poisonous plants and animals also exist in most parts of the country. Therefore, acute poisonings, either intentional or accidental and also drug abuse/addiction are common in Iran. In spite of these difficulties there is no center for poison control and surveillance in this country to gather information and analyse data. The files of a systematic randomised ten percent of all hospital‐referred poisoned patients from 21 March 1993 to 20 March 2000 in Imam Reza (p) University Hospital of Mashhad (71589 cases) were screened retrospectively. Young adults (40.3%) and school children (22.9%) were the most vulnerable group. Mean age was 22.3 (S.D. 14.38) years with a minimum of less than one and a maximum of 98 years old. A female predominance was found (53.4%). Intentional poisoning was more common (54.4%) than accidental exposures (45.2%). Fourteen cases were classified as criminal poisoning. 79.7% of exposures were via ingestion, followed by dermal exposures (14.1%), and inhalation (6.2%). The majority (83.7%) of patients were from urban areas. Most patients (68.6%) were treated in the Emergency Toxicology Clinic and discharged, 19.2% were temporarily hospitalized and 11.3% were hospitalized for 24 hr. Main groups of poisons were pharmaceuticals (61.4%), chemicals (22.8%), and natural toxins (16.6%). The overall number of poisoned patients was higher in spring and summer (62.8%). In conclusion, acute poisonings, particularly self‐poisonings, are common in Iran. Since medical documentation is not routinely provided in this country the results of this retrospective study can be used for surveillance. Establishment of fluent data gathering and analysis within the local health system are challenges for the future.
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