同时双外直流电休克技术治疗伴发心脏病难治性房颤。

Mehmet Kabukcu, Fatih Demircioglu, Ekrem Yanik, Kenan Minareci, Filiz Ersel-Tüzüner
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引用次数: 24

摘要

心房颤动(AF)已经用经胸直流电击治疗,但在5-30%的患者中,该程序不能恢复窦性心律(SR)。我们假设,对胸部施加高能冲击波可以克服电击对心房穿透不足的问题。本研究的目的是评估使用同步双体外除颤器治疗难治性房颤合并心血管疾病的疗效。15例(平均年龄65 +/- 8岁)难治性房颤到标准直流复律(CV)的患者使用双体外除颤器接受了高能直流电击。所有患者均伴有心脏病。华法林和胺碘酮(600 mg/天),在DC CV前给予至少三周的持续时间。静脉注射咪达唑仑镇静。将两个除颤器拨片置于胸壁前后,取右侧侧卧位。除颤器与R波同步,同时给予患者720焦耳的能量。直流休克后持续给予胺碘酮200 mg/d维持sr, 13例患者获得窦性心律。11例患者窦性心律持续6个月。肌酸激酶MB分数在4 (22 +/- 4 IU/L)和12小时(18 +/- 4 IU/L)时正常。没有患者出现明显的血流动力学损害或充血性心力衰竭,更高的房室传导阻滞,中风或短暂性脑缺血事件。结果表明,使用双体外除颤器进行高能量直流电击是一种有效且安全的治疗难治性房颤的方法。我们认为该方法应在心房复律之前进行。
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Simultaneous double external DC shock technique for refractory atrial fibrillation in concomitant heart disease.

Atrial fibrillation (AF) has been treated with DC shocks delivered transthoracically, but in 5-30% of patients, the procedures fail to restore sinus rhythm (SR). We hypothesized that applying high energy shock waves to the chest may overcome the inadequate penetration of electrical shock to the atrium. The aim of this study was to evaluate the efficacy of higher energy external DC shock for the treatment of refractory AF coexisting with cardiovascular disease using a synchronized double external defibrillator. Fifteen patients (mean age 65 +/- 8) with refractory AF to standard DC cardioversion (CV) underwent higher energy DC shock using a double external defibrillator. Concomitant heart disease was present in all patients. Warfarin and amiodarone (600 mg/day), were administered for at least three weeks duration before DC CV. Sedation was performed with IV midazolam. Two defibrillator paddles were positioned on the anterior and posterior chest wall in a right lateral decubitus position. Defibrillators were synchronized to the R waves and simultaneously 720 joules of energy was administered to the patients. Amiodarone (200 mg/day) was continuously administered after DC shock to maintain SR. Sinus rhythm was obtained in 13 patients. Sinus rhythm was persistent in 11 patients for six months duration. Creatine kinase MB fractions were normal at 4 (22 +/- 4 IU/L) and 12 hours (18 +/- 4 IU/L). None of the patients developed significant hemodynamic compromise or congestive heart failure, higher AV block, stroke, or transient ischemic cerebral events. The results indicate that higher energy DC shock application using a double external defibrillator is an effective and safe method for the cardioversion of refractory AF. We believe this procedure should be performed before internal atrial cardioversion.

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