Haiwei Xu , Xiaotang Fan , Jun Tang , Guangji Zhou , Li Yang , Xuan Wu , Shingyong Liu , Jifu Qu , Hui Yang
{"title":"从培养的小鼠胚胎干细胞生成神经前体细胞的改进方法","authors":"Haiwei Xu , Xiaotang Fan , Jun Tang , Guangji Zhou , Li Yang , Xuan Wu , Shingyong Liu , Jifu Qu , Hui Yang","doi":"10.1016/j.brainresprot.2005.03.004","DOIUrl":null,"url":null,"abstract":"<div><p>The pluripotency and high proliferative capacity of embryonic stem (ES) cells make them an attractive source of different cell types for biomedical research and cell replacement therapies. It has been demonstrated that ES cells can be induced into neural precursor cells (NPCs) under conditions. NPCs can be expanded in large numbers for significant periods of time to provide a reliable source of cells for transplantation in neurodegenerative disorders and injury of the central nervous system. This study describes a modified method for generation of NPCs from cultured mouse ES cells.</p></div>","PeriodicalId":79477,"journal":{"name":"Brain research. Brain research protocols","volume":"15 1","pages":"Pages 52-58"},"PeriodicalIF":0.0000,"publicationDate":"2005-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.brainresprot.2005.03.004","citationCount":"12","resultStr":"{\"title\":\"A modified method for generation of neural precursor cells from cultured mouse embryonic stem cells\",\"authors\":\"Haiwei Xu , Xiaotang Fan , Jun Tang , Guangji Zhou , Li Yang , Xuan Wu , Shingyong Liu , Jifu Qu , Hui Yang\",\"doi\":\"10.1016/j.brainresprot.2005.03.004\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>The pluripotency and high proliferative capacity of embryonic stem (ES) cells make them an attractive source of different cell types for biomedical research and cell replacement therapies. It has been demonstrated that ES cells can be induced into neural precursor cells (NPCs) under conditions. NPCs can be expanded in large numbers for significant periods of time to provide a reliable source of cells for transplantation in neurodegenerative disorders and injury of the central nervous system. This study describes a modified method for generation of NPCs from cultured mouse ES cells.</p></div>\",\"PeriodicalId\":79477,\"journal\":{\"name\":\"Brain research. Brain research protocols\",\"volume\":\"15 1\",\"pages\":\"Pages 52-58\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2005-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/j.brainresprot.2005.03.004\",\"citationCount\":\"12\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Brain research. Brain research protocols\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1385299X05000309\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Brain research. Brain research protocols","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1385299X05000309","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
A modified method for generation of neural precursor cells from cultured mouse embryonic stem cells
The pluripotency and high proliferative capacity of embryonic stem (ES) cells make them an attractive source of different cell types for biomedical research and cell replacement therapies. It has been demonstrated that ES cells can be induced into neural precursor cells (NPCs) under conditions. NPCs can be expanded in large numbers for significant periods of time to provide a reliable source of cells for transplantation in neurodegenerative disorders and injury of the central nervous system. This study describes a modified method for generation of NPCs from cultured mouse ES cells.
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