甲型肝炎疫苗接种——以监狱为基础的解决方案应对社区爆发?

R L Gilbert, T O'Connor, S Mathew, K Allen, M Piper, O N Gill
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摘要

2001年12月,在南约克郡发现甲型肝炎病例有所增加。病例主要是报告使用注射毒品的年轻男性。2002年11月实施了以社区为基础的疫苗接种规划,但新病例继续发生。2003年3月,在当地监狱开展了为期四周的疫苗接种运动。1236名囚犯(91%)接种了疫苗。三分之二(895/ 1363)的囚犯来自受疫情影响的地区,52%(465/895)的囚犯报告注射毒品。注射者的中位年龄为25岁。2003年8月,南约克郡停止呈报甲型肝炎个案。虽然这一次监狱疫苗接种运动的实施可能太迟,未能对当地的爆发产生重大影响,但当地大量年轻男性注射者成功地接种了疫苗。这表明,以监狱为基础的干预措施提供了一种潜在的有效方法,可以对注射吸毒者进行免疫接种,并阻断以社区为基础的爆发。
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Hepatitis A vaccination--a prison-based solution for a community-based outbreak?

In December 2001, an increase in cases of hepatitis A was observed in South Yorkshire. Cases were predominantly young males who reported injecting drug use. A community-based vaccination programme was introduced in November 2002, but new cases continued to occur. In March 2003, a vaccination campaign was implemented in the local prison for a four-week period. One thousand two hundred and thirty-six (91%) prisoners were vaccinated. Two thirds (895/1,363) of the prisoners came from the area affected by the outbreak and 52% (465/895) reported injecting drugs. The median age of injectors was 25 years. Notifications of cases of hepatitis A from South Yorkshire ceased in August 2003. Although on this occasion the prison vaccination campaign was probably implemented too late to have had a significant impact on the local outbreak, a large number of young male injectors from the local area were successfully vaccinated. This suggests that a prison-based intervention offers a potentially effective way of immunising the IDU population and interrupting a community-based outbreak.

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