移植后肝静脉闭塞性疾病:发病机制、诊断和治疗。

Reviews in clinical and experimental hematology Pub Date : 2004-06-01

Vincent Ho, Parisa Momtaz, Colleen Didas, Martha Wadleigh, Paul Richardson

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摘要

肝静脉闭塞性疾病(VOD)是造血干细胞移植(SCT)后最重要的并发症之一，严重时死亡率很高。本文综述了VOD的发病机制和临床特点，并概述了内皮细胞损伤的作用和危险因素。讨论了治疗和预防的研究现状。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Post-transplant hepatic veno-occlusive disease: pathogenesis, diagnosis and treatment.

Hepatic veno-occlusive disease (VOD) is one of the most important complications following hematopoietic stem cell transplantation (SCT) and is associated with a very high mortality when severe. This review addresses the pathogenesis and clinical features of VOD and outlines the role on endothelial cell injury and risk factors. The current status of research for both treatment and prevention are discussed.

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Reviews in clinical and experimental hematology

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