流行病学中的因果思维和因果语言:在细节中。

Robert Lipton, Terje Ødegaard
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引用次数: 46

摘要

尽管流行病学必然涉及阐明因果过程,但我们认为,在描述了流行病学结果之后,几乎没有实际需要将其明确标记为因果(或非因果)。这样做是一种惯例,它模糊了流行病学作为公共卫生实践重要组成部分的宝贵核心工作。我们讨论了另一种方法,强调在预测和干预方面独立于明确的形而上学因果主张的研究结果的公共卫生“使用价值”。以吸烟和肺癌为例,特别关注1964年卫生局局长关于吸烟的原始报告和2004年发布的新版本。其目的是帮助流行病学家关注研究的相关含义,从公共卫生的角度来看,这在很大程度上需要预测和干预的能力。进一步的讨论将集中于区分因果语言的技术/实际用途的重要性,如可能用于结构方程或边际结构建模,以及更基本的原因概念。我们表明,统计/流行病学结果,如“每天吸两包烟会使肺癌的风险增加10倍”,本身就是一种因果论证,不需要诸如“吸烟导致肺癌”等相对模糊的语言的额外支持。我们将表明,使用后一种说法所引起的混淆不仅仅是语义学上的。我们的目标是让研究人员对他们的研究力量更有信心,在不诉诸形而上学/不受支持的原因概念的情况下,讲述一个令人信服的故事。
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Causal thinking and causal language in epidemiology: it's in the details.

Although epidemiology is necessarily involved with elucidating causal processes, we argue that there is little practical need, having described an epidemiological result, to then explicitly label it as causal (or not). Doing so is a convention which obscures the valuable core work of epidemiology as an important constituent of public health practice. We discuss another approach which emphasizes the public health "use value" of research findings in regard to prediction and intervention independent from explicit metaphysical causal claims. Examples are drawn from smoking and lung cancer, with particular focus on the original 1964 Surgeon General's report on smoking and the new version released in 2004. The intent is to help the epidemiologist focus on the pertinent implications of research, which, from a public health point of view, in large part entails the ability to predict and to intervene. Further discussion will center on the importance of differentiating between technical/practical uses of causal language, as might be used in structural equations or marginal structural modeling, and more foundational notions of cause. We show that statistical/epidemiological results, such as "smoking two packs a day increases risk of lung cancer by 10 times" are in themselves a kind of causal argument that are not in need of additional support from relatively ambiguous language such as "smoking causes lung cancer." We will show that the confusion stemming from the use of this latter statement is more than mere semantics. Our goal is to allow researchers to feel more confident in the power of their research to tell a convincing story without resorting to metaphysical/unsupportable notions of cause.

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