[房间隔动脉瘤:真正的栓塞源?]。

Scipione Carerj, Concetta Zito, Smeralda Oliva, Giuseppe Tassone, Francesco Luzza, Giuseppe Oreto, Francesco Arrigo
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摘要

房间隔动脉瘤(ASA)是一种公认的心脏异常,临床意义不确定。它早期被报道为尸检时的意外发现,但它也可以通过超声心动图技术在活着的病人中诊断出来。ASA与局灶性脑缺血事件之间存在关联。然而,ASA作为脑缺血危险因素的作用尚不明确。几项研究表明,在原因不明的脑缺血事件后,经食管超声心动图检查的患者中ASA的比例明显更高。然而,ASA通常与其他心脏异常相关,如卵圆孔未闭、房间隔缺损、二尖瓣脱垂或心房心律失常。由于这些异常也可能是心脏栓塞的来源,因此独立评估ASA的栓塞潜力更加困难。在这篇综述中,我们查阅了大多数关于这一主题的论文,试图确定卒中患者中ASA的患病率,以及这种异常如何成为脑血管事件复发的危险因素。
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[Atrial septal aneurysm: a true embolic source?].

Atrial septal aneurysm (ASA) is a well-recognized cardiac abnormality of uncertain clinical significance. It has early been reported as an unexpected finding during autopsy, but it may also be diagnosed in living patients by echocardiographic techniques. An association between ASA and focal cerebral ischemic events has been suggested. Nevertheless, the role of ASA as a risk factor for cerebral ischemia is poorly defined. Several studies have demonstrated a significantly higher proportion of ASA in the patients referred for transesophageal echocardiography after a cerebral ischemic event of unknown cause. However, ASA is often associated with other cardiac abnormalities such as patent foramen ovale, atrial septal defects, as well as mitral valve prolapse or atrial arrhythmias. Due to the fact that these abnormalities are also possible sources of cardiac emboli it is even more difficult to assess the embolic potential of an ASA, independently. In this review, we have examined most of the papers on this topic to try to define the prevalence of ASA in the stroke patients and how this abnormality could be a risk factor for recurrences of cerebrovascular events.

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