在卡塔尔的印度侨民的血脂分布和血脂异常的流行。

IF 5.9 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY Journal of Lipids Pub Date : 2021-03-05 eCollection Date: 2021-01-01 DOI:10.1155/2021/8866784
R Nirwan, D Singh
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引用次数: 5

摘要

背景:血脂异常是心血管疾病(CVD)的重要危险因素。如果在生命的早期阶段发现和管理,可以降低脆弱人群中与心血管疾病相关的发病率和死亡率。在卡塔尔的94个外籍国籍中,印度人是最突出的单一国籍,占总人口的21.8%(2019年为2,773,885人)。本研究旨在确定在卡塔尔的印度人的血脂状况。研究设计。我们对2018年10月17日至10月在卡塔尔一家私人医疗机构就诊的印度外籍人士的血脂检测数据进行了一项观察性回顾性研究,以评估血脂的性别和年龄特异性分布以及血脂异常的患病率。结果:在4483名印度侨民中(3891名男性和592名女性),男性的总胆固醇(TC)、甘油三酯(TG)和低密度脂蛋白胆固醇(LDL-C)的平均(SD) mg/dL水平(196.9(40.6)、TG 168.9(114.6)和LDL-C 122.9 (37.2) mg/dL高于女性(185(38.1)、TG 117.7(78.2)和LDL-C 114.1 (31.1) mg/dL, p值< 0.0001。利用预定义的国家胆固醇教育计划-成人治疗小组III (NCEP ATP III)限制对血脂异常进行分类;男性中TC、TG和LDL-C升高的发生率分别为44.7%、45.8%和40.9%,而女性分别为31.6%、22%和28.7%。然而,女性的平均高密度脂蛋白胆固醇(HDL-C)水平高于男性,分别为47.1 (9.8)mg/dL和40.6 (8.3)mg/dL, p值< 0.05,血脂异常、低HDL-C的患病率在女性中也高于男性65.7%和48.9%。随着年龄的增长,男性的平均脂质水平呈下降趋势,女性的血脂异常、高TC、高TG、高LDL-C患病率呈上升趋势(p值< 0.0001)。平均HDL-C胆固醇增加,血脂异常、低HDL-C患病率随着年龄的增长而下降。结论:我们的研究结果表明,在年轻年龄组中,印度外籍男性的平均脂质水平和动脉粥样硬化性血脂异常的患病率高于女性。筛查程序和宣传活动必须启动,以防止早期发作的血脂异常引起的动脉粥样硬化导致心血管疾病。未来需要对照研究来估计在卡塔尔的印度移民中血脂异常的患病率。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Distribution of Lipids and Prevalence of Dyslipidemia among Indian Expatriates in Qatar.

Background: Dyslipidemia is a significant risk factor for cardiovascular diseases (CVD). If detected and managed in the early stages of life, can reduce morbidity and mortality associated with CVD in a vulnerable population. Out of the 94 expatriate nationalities in Qatar, Indians constitute the most prominent single nationality, accounting for 21.8% of the total population (2,773,885 in 2019). This study aims to determine the status of the lipid profile among Indians in Qatar. Study Design. We conducted an observational retrospective study on lipid profile test data of Indian expatriates visiting a private healthcare facility in Qatar from Oct 17 to Oct 2018 to evaluate the gender and age-specific distribution of lipids and the prevalence of dyslipidemia.

Results: Among the total 4483 Indian expatriates (3891 men and 592 women), the mean (SD) mg/dL levels of total cholesterol (TC), triglycerides (TG), and low-density lipoprotein cholesterol (LDL-C) were higher in men TC 196.9 (40.6), TG 168.9 (114.6), and LDL-C 122.9 (37.2) mg/dL compared to women TC 185 (38.1), TG 117.7 (78.2), and LDL-C 114.1 (31.1) mg/dL, p value < 0.0001. Utilizing predefined National Cholesterol Education Program-Adult Treatment Panel III (NCEP ATP III) limits to categorize dyslipidemias; the greater prevalence of elevated TC, TG, and LDL-C was noted in men 44.7%, 45.8%, and 40.9% than women 31.6%, 22%, and 28.7%, respectively. However, women had higher levels of mean high-density lipoprotein cholesterol (HDL-C) as 47.1 (9.8) mg/dL vs. 40.6 (8.3) mg/dL in men, p value < 0.05, the prevalence of dyslipidemia, low HDL-C was also more 65.7% vs. 48.9% in women than men. With age, men showed a declining trend while women showed a rising trend for mean lipid levels as well as for the prevalence of dyslipidemia, high TC, TG, and LDL-C (p value < 0.0001). The mean HDL-C cholesterol increased, and the prevalence of dyslipidemia, low HDL-C decreased with age in both the genders.

Conclusion: Our results demonstrate the higher mean lipid levels and prevalence of atherogenic dyslipidemia among Indian expatriate men than women counterparts at the younger age group. The screening programs and awareness campaigns must be initiated to prevent the early onset of dyslipidemia induced atherosclerosis leading to CVD. Future controlled studies are needed to estimate the prevalence of dyslipidemias among Indian migrants in Qatar.

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来源期刊
Journal of Lipids
Journal of Lipids BIOCHEMISTRY & MOLECULAR BIOLOGY-
自引率
0.00%
发文量
7
审稿时长
12 weeks
期刊介绍: Journal of Lipids is a peer-reviewed, Open Access journal that publishes original research articles and review articles related to all aspects of lipids, including their biochemistry, synthesis, function in health and disease, and nutrition. As an interdisciplinary journal, Journal of Lipids aims to provide a forum for scientists, physicians, nutritionists, and other relevant health professionals.
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