Iwona Stelmach, Malgorzata Podsiadłowicz-Borzecka, Tomasz Grzelewski, Pawel Majak, Wlodzimierz Stelmach, Joanna Jerzyńska, Marta Popławska, Jaroslaw Dziadek
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Humoral and cellular immunity in children with Mycoplasma pneumoniae infection: a 1-year prospective study.
To determine whether children have persistent abnormalities in cellular and humoral immunity development after acute Mycoplasma pneumoniae infection, serum immunoglobulin G (IgG), IgA, IgM, and IgE levels and lymphocyte phenotypes were determined. There were no changes in the levels of IgG, IgM, IgA, or CD4+ or CD19+ lymphocytes that were measured in M. pneumoniae-positive patients after 3 months or after 12 months, but there were increases in these in M. pneumoniae-negative patients. Serum IgE increased in M. pneumoniae-positive patients. We have shown alterations in immunity development after M. pneumoniae infection.
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