肺动脉高压:超声心动图评估。

Susanna Sciomer, Roberto Badagliacca, Francesco Fedele
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摘要

肺动脉高压(PAH)是一种以血管阻力升高为特征的临床疾病,预后较差,通常在晚期诊断。超声心动图对多环芳烃的评估包括早期疾病检测和心脏功能评估,以便在疾病的早期阶段引入更准确的监测,并有助于晚期疾病的预后分层。检测包括肺动脉收缩压(PASP)的估计。对于正态分布的定义没有明确的共识,但36 mmHg的PASP被广泛认为是轻度PAH的临界值,需要更积极的监测来发现进一步的进展。功能性心脏评估需要准确描述PAH发展后的形态学和血流动力学变化,包括对尺寸参数、心室相互依赖性、心内血流模式和右心室收缩性能的描述。对这些问题的有效评估可以对心功能进行有用的评估,从而支持临床上对心力衰竭病情的定义。
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Pulmonary hypertension: echocardiographic assessment.

Pulmonary arterial hypertension (PAH) is a clinical condition characterized by elevated vascular resistance, associated with a poor prognosis and usually diagnosed in late stage. Echocardiographic assessment of PAH includes early disease detection and functional heart evaluation, in order to introduce a more accurate surveillance at an early stage of the disease and to contribute to prognostic stratification of advanced disease. Detection involves pulmonary artery systolic pressure (PASP) estimation. There is no clear consensus on defining normal distribution, but a PASP of 36 mmHg has been widely assumed as a cut-off value for mild PAH, requiring a more aggressive surveillance to detect further progression. Functional heart evaluation requires an accurate characterization of morphologic and hemodynamic changes, secondary to PAH development, which involves description of dimensional parameters, ventricular interdependency, intracardiac flow patterns, and right ventricular systolic performance. A valid assessment of these issues results in a useful evaluation of cardiac function, supporting clinical context in defining heart failure condition.

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