猴免疫缺陷病毒引起的猕猴眼部病理表现。

J K Johnson, K A Warren, N E J Berman, O Narayan, E B Stephens, S V Joag, R Raghavan, J K Marcario, P D Cheney
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引用次数: 2

摘要

猴免疫缺陷病毒已被证明可引起猕猴获得性免疫缺陷综合征。从临床检查和眼底摄影收集的数据表明,慢病毒能够诱导猕猴脉络膜病变和视网膜出血。这些发现证明了猕猴眼作为人类艾滋病患者视网膜病理模型的潜在价值。
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Manifestations of SIV-induced ocular pathology in macaque monkeys.

Simian immunodeficiency virus has been shown to cause acquired immunodeficiency syndrome in macaque monkeys. Data gathered from clinical examination and fundus photography have shown that the lentivirus is capable of the induction of choroidal lesions and retinal hemorrhages in the macaque. These findings demonstrate the potential value of the macaque monkey eye as a model of the retinal pathology routinely seen in human AIDS patients.

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