Genovefa D Kolovou, Katherine K Anagnostopoulou, Antonis N Pavlidis, Klelia D Salpea, Stella A Iraklianou, Ioannis S Hoursalas, Dimitri P Mikhailidis, Dennis V Cokkinos
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引用次数: 16
摘要
背景:餐后高脂血症可能是血管危险的一个预测因子。设计:我们对患有代谢综合征(MetS)的男性(n=41)和女性(n=21)进行口服脂肪耐量试验(OFTT)后的餐后脂血症进行评估。方法:测定脂肪负荷前及负荷后2、4、6、8 h的甘油三酯(TG)水平。结果:男性在脂肪负荷8小时后表现出更大的血浆TG反应(284+/-117 vs 224+/-126 mg/dl, P=0.029)。只有空腹TG水平能显著预测曲线下TG面积(AUC)和增量AUC。结论:男性有更明显的餐后高甘油三酯血症，似乎有延迟TG清除。
Metabolic syndrome and gender differences in postprandial lipaemia.
Background: Postprandial hyperlipidaemia may be a predictor of vascular risk.
Design: We evaluated postprandial lipaemia after an oral fat tolerance test (OFTT) in men (n=41) and women (n=21) with metabolic syndrome (MetS).
Methods: Triglyceride (TG) levels were measured before and 2, 4, 6 and 8 h after the fat load.
Results: Men showed a greater plasma TG response 8 h after the fat load (284+/-117 versus 224+/-126 mg/dl, P=0.029). Only fasting TG levels significantly predicted the TG area under the curve (AUC) and incremental AUC.
Conclusions: Men had a more pronounced postprandial hypertriglyceridaemia and seem to have delayed TG clearance.
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