{"title":"斑马鱼基因表达的小分子开关","authors":"Young-Tae Chang","doi":"10.1038/nchembio0307-135","DOIUrl":null,"url":null,"abstract":"The zebrafish is a highly promising model system for vertebrate genetics study, but the temporal control of gene expression has remained underdeveloped. A new chemical genetic system using a small-molecule switch for protein synthesis promises to increase the usefulness of the zebrafish as a vertebrate model system.","PeriodicalId":18832,"journal":{"name":"Nature chemical biology","volume":null,"pages":null},"PeriodicalIF":12.9000,"publicationDate":"2007-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1038/nchembio0307-135","citationCount":"1","resultStr":"{\"title\":\"Small-molecule switch for zebrafish gene expression\",\"authors\":\"Young-Tae Chang\",\"doi\":\"10.1038/nchembio0307-135\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The zebrafish is a highly promising model system for vertebrate genetics study, but the temporal control of gene expression has remained underdeveloped. A new chemical genetic system using a small-molecule switch for protein synthesis promises to increase the usefulness of the zebrafish as a vertebrate model system.\",\"PeriodicalId\":18832,\"journal\":{\"name\":\"Nature chemical biology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":12.9000,\"publicationDate\":\"2007-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1038/nchembio0307-135\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nature chemical biology\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://www.nature.com/articles/nchembio0307-135\",\"RegionNum\":1,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"BIOCHEMISTRY & MOLECULAR BIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature chemical biology","FirstCategoryId":"99","ListUrlMain":"https://www.nature.com/articles/nchembio0307-135","RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"BIOCHEMISTRY & MOLECULAR BIOLOGY","Score":null,"Total":0}
Small-molecule switch for zebrafish gene expression
The zebrafish is a highly promising model system for vertebrate genetics study, but the temporal control of gene expression has remained underdeveloped. A new chemical genetic system using a small-molecule switch for protein synthesis promises to increase the usefulness of the zebrafish as a vertebrate model system.
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