{"title":"噬菌体暴露于有机溶剂后感染性丧失的简单双过渡模型","authors":"Teruhiko Matsubara , Wakako Emoto , Katsuhiro Kawashiro","doi":"10.1016/j.bioeng.2007.02.002","DOIUrl":null,"url":null,"abstract":"<div><p>The effect of water-miscible organic solvents on the stability of filamentous phages displaying a random peptide library was investigated. A kinetic analysis of the time course of viral infectivity indicated that the transition between the noninfectious and infectious form was directly related to the concentration of organic solvent.</p></div>","PeriodicalId":80259,"journal":{"name":"Biomolecular engineering","volume":"24 2","pages":"Pages 269-271"},"PeriodicalIF":0.0000,"publicationDate":"2007-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.bioeng.2007.02.002","citationCount":"10","resultStr":"{\"title\":\"A simple two-transition model for loss of infectivity of phages on exposure to organic solvent\",\"authors\":\"Teruhiko Matsubara , Wakako Emoto , Katsuhiro Kawashiro\",\"doi\":\"10.1016/j.bioeng.2007.02.002\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>The effect of water-miscible organic solvents on the stability of filamentous phages displaying a random peptide library was investigated. A kinetic analysis of the time course of viral infectivity indicated that the transition between the noninfectious and infectious form was directly related to the concentration of organic solvent.</p></div>\",\"PeriodicalId\":80259,\"journal\":{\"name\":\"Biomolecular engineering\",\"volume\":\"24 2\",\"pages\":\"Pages 269-271\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2007-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/j.bioeng.2007.02.002\",\"citationCount\":\"10\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Biomolecular engineering\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1389034407000214\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biomolecular engineering","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1389034407000214","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
A simple two-transition model for loss of infectivity of phages on exposure to organic solvent
The effect of water-miscible organic solvents on the stability of filamentous phages displaying a random peptide library was investigated. A kinetic analysis of the time course of viral infectivity indicated that the transition between the noninfectious and infectious form was directly related to the concentration of organic solvent.
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