雄性哺乳仔猪去势前局部麻醉的效果。

A Zankl, M Ritzmann, S Zöls, K Heinritzi
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引用次数: 0

摘要

目的观察不同局部麻醉剂(盐酸普鲁卡因、盐酸普鲁卡因+肾上腺素、盐酸利多卡因)对4 ~ 6日龄公仔猪去势的影响。对照组(I-IV)与去势组(V-IX)相似,但未进行去势处理。I组和V组在去势/固定前15分钟将仔猪固定为注射,不给药。标准注射量为每只睾丸0.5 ml。5组采用胃内局部麻醉,2组采用胃内局部麻醉。在去势/固定前、1小时、4小时和24小时采集血样。分析血清皮质醇水平,以确定疼痛引起的神经内分泌应激反应。为证明组织耐受性,测定了肌酸激酶(CK)和天冬氨酸氨基转移酶(AST)的浓度。去势后第1天、第7天和第14天采用伤口评分法评估伤口愈合情况。第1至第4组血清皮质醇水平未见升高。相反,去势组(V-IX)平均皮质醇浓度在去势1小时后显著升高。去势药物组(VI-IX)的皮质醇浓度与未给药对照组(V)相当,甚至更高。CK和AST的测定表明,局部麻醉剂的应用没有造成组织损伤。去势前的局部麻醉对伤口愈合过程没有任何影响。本研究结果表明,局部麻醉药注射具有良好的组织耐受性,但术前注射盐酸普鲁卡因或盐酸利多卡因减轻去势疼痛的主张并不合理。
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[The efficacy of local anaesthetics administered prior to castration of male suckling piglets].

Objective of this study was to examine the efficacy of various local anaesthetics (Procaine Hydrochloride, Procaine Hydrochloride + Epinephrin, Lidocaine Hydrochloride) used in castration of four to six day old male piglets. Animals of the control groups (I-IV) were treated analogous to the castration groups (V-IX) but not castrated. In groups I and V 15 minutes prior to castration/fixation the piglets were fixed as for injection but not medicated. The injection volume was standardised to 0.5 ml per testes. Local anaesthetics were applicated intratesticularly in five groups and intrascrotarly in two groups. Blood samples were taken shortly before and one, four and 24 hours after castration/fixation. The serum cortisol level was analysed to determine pain induced neuroendocrine stress reaction. To proof the tissue tolerance creatinkinase-(CK) and aspartataminotransferase-(AST) concentration were analysed. One, seven and 14 days after castration the healing process were evaluated by a wound score. Groups I to IV did not show any increase of the serum cortisol level. Contrary one hour after castration the average cortisol concentration of castration groups (V-IX) rose significantly. Cortisol concentration of the medicated castration groups (VI-IX) showed a comparable or even higher cortisol level as the not medicated control group (V). Determination of CK and AST indicated no tissue damage of the application of the local anaesthetics. The administration of local anaesthetics prior to the castration did not have any effect on the wound healing process. The results of this study lead to the conclusion that injection of local anaesthetics show a good tissue tolerance but the call for reduction of the castration pain by presurgical injection of Procaine Hydrochloride or Lidocaine Hydrochloride is not justified.

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