[血脂异常和腹部肥胖:机制和特征(第一部分)]。

M Farnier
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引用次数: 0

摘要

典型的与腹部肥胖相关的血脂异常以代谢致动脉粥样硬化三征为特征,包括甘油三酯升高、低高密度脂蛋白胆固醇和小密度低密度脂蛋白过多。所有这些脂质异常都会增加心脏代谢风险,并且是由内脏脂肪组织过量引起的。这种多余的脂肪组织似乎是与腹部肥胖相关的血脂异常的直接起源,导致更多的游离脂肪酸流入肝脏,并导致胰岛素抵抗。
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[Dyslipidemia and abdominal obesity: mechanisms and characteristics (Part I)].

The dyslipidemia classically associated with abdominal obesity is characterised by a metabolic atherogenic triad including an elevation of triglycerides, a low HDL-cholesterol and an excess of small dense LDL fractions. All of these lipid anomalies contribute to an increased cardio-metabolic risk, and are engendered by an excess of visceral adipose tissue. This excess adipose tissue seems to be the direct origin of the dyslipidemia associated with abdominal obesity, causing more free fatty acids to flow into the liver and contributing to insulin resistance.

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