临床生物信息学的网络资源。

Anthony M Joshua, Paul C Boutros
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引用次数: 4

摘要

在后人类基因组计划时代,意识到通过互联网可获得的资源对分子生物学家和临床医生都是至关重要的。本章中描述的主要数据库和分析工具的概述对于理解产生假设,实验和得出结论的原则非常重要。类似地,对这些资源的术语的介绍通常有助于它们在实践中的使用和采用。本章涵盖了NCBI/ Entrez, Ensembl和UCSC等数据库资源以及序列比对,启动子分析和分子相互作用的分析工具。
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Web-based resources for clinical bioinformatics.

In the post-Human Genome Project era, awareness of the resources available through the internet is essential to both molecular biologists and clinicians. An overview of the main databases and analytical tools described in this chapter is important to understand the principles upon which hypotheses are generated, experiments are based and conclusions reached. Similarly, an introduction to the terminology of these resources often facilitates their use and adoption into practice. This chapter covers database resources such as NCBI/ Entrez, Ensembl and UCSC as well as analytical tools for sequence alignment, promoter analysis and molecular interactions.

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